diff --git a/homeassistant/package_constraints.txt b/homeassistant/package_constraints.txt
index 1f7c6bd61cc..e3f80f1b82d 100644
--- a/homeassistant/package_constraints.txt
+++ b/homeassistant/package_constraints.txt
@@ -98,11 +98,6 @@ enum34==1000000000.0.0
 typing==1000000000.0.0
 uuid==1000000000.0.0
 
-# regex causes segfault with version 2021.8.27
-# https://bitbucket.org/mrabarnett/mrab-regex/issues/421/2021827-results-in-fatal-python-error
-# This is fixed in 2021.8.28
-regex==2021.8.28
-
 # httpx requires httpcore, and httpcore requires anyio and h11, but the version constraints on
 # these requirements are quite loose. As the entire stack has some outstanding issues, and
 # even newer versions seem to introduce new issues, it's useful for us to pin all these
diff --git a/script/gen_requirements_all.py b/script/gen_requirements_all.py
index f887f8113a7..aa92cacb237 100755
--- a/script/gen_requirements_all.py
+++ b/script/gen_requirements_all.py
@@ -120,11 +120,6 @@ enum34==1000000000.0.0
 typing==1000000000.0.0
 uuid==1000000000.0.0
 
-# regex causes segfault with version 2021.8.27
-# https://bitbucket.org/mrabarnett/mrab-regex/issues/421/2021827-results-in-fatal-python-error
-# This is fixed in 2021.8.28
-regex==2021.8.28
-
 # httpx requires httpcore, and httpcore requires anyio and h11, but the version constraints on
 # these requirements are quite loose. As the entire stack has some outstanding issues, and
 # even newer versions seem to introduce new issues, it's useful for us to pin all these