diff --git a/homeassistant/components/ssdp/manifest.json b/homeassistant/components/ssdp/manifest.json
index 0fecbc01282..465c1ce3cbf 100644
--- a/homeassistant/components/ssdp/manifest.json
+++ b/homeassistant/components/ssdp/manifest.json
@@ -2,10 +2,7 @@
   "domain": "ssdp",
   "name": "Simple Service Discovery Protocol (SSDP)",
   "documentation": "https://www.home-assistant.io/integrations/ssdp",
-  "requirements": [
-    "defusedxml==0.7.1",
-    "async-upnp-client==0.22.1"
-  ],
+  "requirements": ["async-upnp-client==0.22.1"],
   "dependencies": ["network"],
   "after_dependencies": ["zeroconf"],
   "codeowners": [],
diff --git a/homeassistant/package_constraints.txt b/homeassistant/package_constraints.txt
index 2fce5d7cc7a..878943152fa 100644
--- a/homeassistant/package_constraints.txt
+++ b/homeassistant/package_constraints.txt
@@ -13,7 +13,6 @@ bcrypt==3.1.7
 certifi>=2020.12.5
 ciso8601==2.2.0
 cryptography==3.4.8
-defusedxml==0.7.1
 emoji==1.5.0
 hass-nabucasa==0.50.0
 home-assistant-frontend==20210922.0
diff --git a/requirements_all.txt b/requirements_all.txt
index 48880661cfe..967fc71aa4c 100644
--- a/requirements_all.txt
+++ b/requirements_all.txt
@@ -522,7 +522,6 @@ debugpy==1.4.3
 # homeassistant.components.ihc
 # homeassistant.components.namecheapdns
 # homeassistant.components.ohmconnect
-# homeassistant.components.ssdp
 defusedxml==0.7.1
 
 # homeassistant.components.deluge
diff --git a/requirements_test_all.txt b/requirements_test_all.txt
index bd537b46431..fcea1527eb8 100644
--- a/requirements_test_all.txt
+++ b/requirements_test_all.txt
@@ -318,7 +318,6 @@ debugpy==1.4.3
 # homeassistant.components.ihc
 # homeassistant.components.namecheapdns
 # homeassistant.components.ohmconnect
-# homeassistant.components.ssdp
 defusedxml==0.7.1
 
 # homeassistant.components.denonavr