diff --git a/homeassistant/components/mysensors/manifest.json b/homeassistant/components/mysensors/manifest.json
index 3b7695146ba..6e7a4f9cded 100644
--- a/homeassistant/components/mysensors/manifest.json
+++ b/homeassistant/components/mysensors/manifest.json
@@ -2,7 +2,7 @@
   "domain": "mysensors",
   "name": "MySensors",
   "documentation": "https://www.home-assistant.io/integrations/mysensors",
-  "requirements": ["pymysensors==0.21.0"],
+  "requirements": ["pymysensors==0.22.1"],
   "after_dependencies": ["mqtt"],
   "codeowners": ["@MartinHjelmare", "@functionpointer"],
   "config_flow": true,
diff --git a/requirements_all.txt b/requirements_all.txt
index 0dc5a8fbe9c..f9fd2ce34a7 100644
--- a/requirements_all.txt
+++ b/requirements_all.txt
@@ -1658,7 +1658,7 @@ pymsteams==0.1.12
 pymyq==3.1.4
 
 # homeassistant.components.mysensors
-pymysensors==0.21.0
+pymysensors==0.22.1
 
 # homeassistant.components.netgear
 pynetgear==0.7.0
diff --git a/requirements_test_all.txt b/requirements_test_all.txt
index c81844aac11..28abac33b50 100644
--- a/requirements_test_all.txt
+++ b/requirements_test_all.txt
@@ -1004,7 +1004,7 @@ pymonoprice==0.3
 pymyq==3.1.4
 
 # homeassistant.components.mysensors
-pymysensors==0.21.0
+pymysensors==0.22.1
 
 # homeassistant.components.netgear
 pynetgear==0.7.0