diff --git a/homeassistant/components/vizio/config_flow.py b/homeassistant/components/vizio/config_flow.py
index b6d6d9bfb05..40f71adda12 100644
--- a/homeassistant/components/vizio/config_flow.py
+++ b/homeassistant/components/vizio/config_flow.py
@@ -369,6 +369,10 @@ class VizioConfigFlow(config_entries.ConfigFlow, domain=DOMAIN):
             discovery_info[CONF_DEVICE_CLASS],
             session=async_get_clientsession(self.hass, False),
         )
+
+        if not unique_id:
+            return self.async_abort(reason="cannot_connect")
+
         await self.async_set_unique_id(unique_id=unique_id, raise_on_progress=True)
         self._abort_if_unique_id_configured()
 
diff --git a/homeassistant/components/vizio/strings.json b/homeassistant/components/vizio/strings.json
index da039b6a89e..adad8406da0 100644
--- a/homeassistant/components/vizio/strings.json
+++ b/homeassistant/components/vizio/strings.json
@@ -34,6 +34,7 @@
     },
     "abort": {
       "already_configured_device": "[%key:common::config_flow::abort::already_configured_device%]",
+      "cannot_connect": "[%key:common::config_flow::error::cannot_connect%]",
       "updated_entry": "This entry has already been setup but the name, apps, and/or options defined in the configuration do not match the previously imported configuration, so the configuration entry has been updated accordingly."
     }
   },
diff --git a/tests/components/vizio/test_config_flow.py b/tests/components/vizio/test_config_flow.py
index 32469fabd05..e966188afd2 100644
--- a/tests/components/vizio/test_config_flow.py
+++ b/tests/components/vizio/test_config_flow.py
@@ -856,6 +856,21 @@ async def test_zeroconf_ignore(
     assert result["type"] == data_entry_flow.RESULT_TYPE_FORM
 
 
+async def test_zeroconf_no_unique_id(
+    hass: HomeAssistantType,
+    vizio_no_unique_id: pytest.fixture,
+) -> None:
+    """Test zeroconf discovery aborts when unique_id is None."""
+
+    discovery_info = MOCK_ZEROCONF_SERVICE_INFO.copy()
+    result = await hass.config_entries.flow.async_init(
+        DOMAIN, context={"source": SOURCE_ZEROCONF}, data=discovery_info
+    )
+
+    assert result["type"] == data_entry_flow.RESULT_TYPE_ABORT
+    assert result["reason"] == "cannot_connect"
+
+
 async def test_zeroconf_abort_when_ignored(
     hass: HomeAssistantType,
     vizio_connect: pytest.fixture,