diff --git a/homeassistant/package_constraints.txt b/homeassistant/package_constraints.txt
index ad03978c6ef..167fe546b35 100644
--- a/homeassistant/package_constraints.txt
+++ b/homeassistant/package_constraints.txt
@@ -114,3 +114,7 @@ backoff<2.0
 # Breaking change in version
 # https://github.com/samuelcolvin/pydantic/issues/4092
 pydantic!=1.9.1
+
+# Breaks asyncio
+# https://github.com/pubnub/python/issues/130
+pubnub!=6.4.0
diff --git a/script/gen_requirements_all.py b/script/gen_requirements_all.py
index 11e88976e83..7b000a30be2 100755
--- a/script/gen_requirements_all.py
+++ b/script/gen_requirements_all.py
@@ -132,6 +132,10 @@ backoff<2.0
 # Breaking change in version
 # https://github.com/samuelcolvin/pydantic/issues/4092
 pydantic!=1.9.1
+
+# Breaks asyncio
+# https://github.com/pubnub/python/issues/130
+pubnub!=6.4.0
 """
 
 IGNORE_PRE_COMMIT_HOOK_ID = (