diff --git a/homeassistant/components/zha/helpers.py b/homeassistant/components/zha/helpers.py
index f70c8a9cb3e..2030ffcdb3d 100644
--- a/homeassistant/components/zha/helpers.py
+++ b/homeassistant/components/zha/helpers.py
@@ -1166,7 +1166,8 @@ CONF_ZHA_OPTIONS_SCHEMA = vol.Schema(
             CONF_CONSIDER_UNAVAILABLE_BATTERY,
             default=CONF_DEFAULT_CONSIDER_UNAVAILABLE_BATTERY,
         ): cv.positive_int,
-    }
+    },
+    extra=vol.REMOVE_EXTRA,
 )
 
 CONF_ZHA_ALARM_SCHEMA = vol.Schema(
diff --git a/tests/components/zha/test_helpers.py b/tests/components/zha/test_helpers.py
index d3392685437..f6dc8291d9f 100644
--- a/tests/components/zha/test_helpers.py
+++ b/tests/components/zha/test_helpers.py
@@ -5,16 +5,23 @@ from typing import Any
 
 import pytest
 import voluptuous_serialize
+from zigpy.application import ControllerApplication
 from zigpy.types.basic import uint16_t
 from zigpy.zcl.clusters import lighting
 
+import homeassistant.components.zha.const as zha_const
 from homeassistant.components.zha.helpers import (
     cluster_command_schema_to_vol_schema,
     convert_to_zcl_values,
+    create_zha_config,
     exclude_none_values,
+    get_zha_data,
 )
 from homeassistant.core import HomeAssistant
 import homeassistant.helpers.config_validation as cv
+from homeassistant.setup import async_setup_component
+
+from tests.common import MockConfigEntry
 
 _LOGGER = logging.getLogger(__name__)
 
@@ -177,3 +184,35 @@ def test_exclude_none_values(
 
     for key in expected_output:
         assert expected_output[key] == obj[key]
+
+
+async def test_create_zha_config_remove_unused(
+    hass: HomeAssistant,
+    config_entry: MockConfigEntry,
+    mock_zigpy_connect: ControllerApplication,
+) -> None:
+    """Test creating ZHA config data with unused keys."""
+    config_entry.add_to_hass(hass)
+
+    options = config_entry.options.copy()
+    options["custom_configuration"]["zha_options"]["some_random_key"] = "a value"
+
+    hass.config_entries.async_update_entry(config_entry, options=options)
+
+    assert (
+        config_entry.options["custom_configuration"]["zha_options"]["some_random_key"]
+        == "a value"
+    )
+
+    status = await async_setup_component(
+        hass,
+        zha_const.DOMAIN,
+        {zha_const.DOMAIN: {zha_const.CONF_ENABLE_QUIRKS: False}},
+    )
+    assert status is True
+    await hass.async_block_till_done()
+
+    ha_zha_data = get_zha_data(hass)
+
+    # Does not error out
+    create_zha_config(hass, ha_zha_data)