diff --git a/targets/TARGET_NUVOTON/TARGET_M480/device/system_M480.c b/targets/TARGET_NUVOTON/TARGET_M480/device/system_M480.c
index 827b92f1b0..1aa070152c 100644
--- a/targets/TARGET_NUVOTON/TARGET_M480/device/system_M480.c
+++ b/targets/TARGET_NUVOTON/TARGET_M480/device/system_M480.c
@@ -88,5 +88,13 @@ void SystemInit (void)
     SPIM_DISABLE_CACHE();
     SPIM_ENABLE_CCM();
     while (! SPIM_IS_CCM_EN());
+    
+#ifndef MBED_CONF_M480_CTRL01_ENABLE
+#define MBED_CONF_M480_CTRL01_ENABLE 1
+#endif
+
+#if (! MBED_CONF_M480_CTRL01_ENABLE)
+    M32(0x4000c018) |= 0x00000080;
+#endif
 }
 /*** (C) COPYRIGHT 2016 Nuvoton Technology Corp. ***/
diff --git a/targets/TARGET_NUVOTON/TARGET_M480/mbed_lib.json b/targets/TARGET_NUVOTON/TARGET_M480/mbed_lib.json
index 198e8de55c..b762bc2b36 100644
--- a/targets/TARGET_NUVOTON/TARGET_M480/mbed_lib.json
+++ b/targets/TARGET_NUVOTON/TARGET_M480/mbed_lib.json
@@ -20,6 +20,10 @@
         "usb-device-hsusbd": {
             "help": "Select high-speed USB device or not",
             "value": 1
+        },
+        "ctrl01-enable": {
+            "help": "Enable control_01",
+            "value": 0
         }
     }
 }