diff --git a/targets/TARGET_STM/USBPhy_STM32.cpp b/targets/TARGET_STM/USBPhy_STM32.cpp
index 63ec3c974b..6a4b0ea8a8 100644
--- a/targets/TARGET_STM/USBPhy_STM32.cpp
+++ b/targets/TARGET_STM/USBPhy_STM32.cpp
@@ -247,6 +247,14 @@ void USBPhyHw::init(USBPhyEvents *events)
     hpcd.Init.use_external_vbus = DISABLE;
 
     __HAL_RCC_USB_OTG_HS_CLK_ENABLE();
+
+    #ifdef __HAL_RCC_USB1_OTG_FS_ULPI_CLK_SLEEP_DISABLE
+        __HAL_RCC_USB1_OTG_FS_ULPI_CLK_SLEEP_DISABLE();
+    #endif
+    #ifdef __HAL_RCC_USB2_OTG_FS_ULPI_CLK_SLEEP_DISABLE
+        __HAL_RCC_USB2_OTG_FS_ULPI_CLK_SLEEP_DISABLE();
+    #endif
+     
     map = PinMap_USB_HS;
 
 #elif (MBED_CONF_TARGET_USB_SPEED == USE_USB_OTG_FS)
@@ -256,6 +264,14 @@ void USBPhyHw::init(USBPhyEvents *events)
     hpcd.Init.speed = PCD_SPEED_FULL;
 
     __HAL_RCC_USB_OTG_FS_CLK_ENABLE();
+
+    #ifdef __HAL_RCC_USB1_OTG_FS_ULPI_CLK_SLEEP_DISABLE
+        __HAL_RCC_USB1_OTG_FS_ULPI_CLK_SLEEP_DISABLE();
+    #endif
+    #ifdef __HAL_RCC_USB2_OTG_FS_ULPI_CLK_SLEEP_DISABLE
+        __HAL_RCC_USB2_OTG_FS_ULPI_CLK_SLEEP_DISABLE();
+    #endif
+     
     map = PinMap_USB_FS;
 
 #elif (MBED_CONF_TARGET_USB_SPEED == USE_USB_NO_OTG)