diff --git a/features/unsupported/USBHost/targets/TARGET_STM/USBHALHost_STM.h b/features/unsupported/USBHost/targets/TARGET_STM/USBHALHost_STM.h
index dd741ecd03..59d3e61f56 100644
--- a/features/unsupported/USBHost/targets/TARGET_STM/USBHALHost_STM.h
+++ b/features/unsupported/USBHost/targets/TARGET_STM/USBHALHost_STM.h
@@ -122,10 +122,17 @@ static gpio_t gpio_powerpin;
 
 void usb_vbus(uint8_t state)
 {
-    if (state == 0) {
-        gpio_write(&gpio_powerpin, USB_POWER_OFF);
-    } else {
-        gpio_write(&gpio_powerpin, USB_POWER_ON);
+    if (gpio_powerpin.reg_set && gpio_powerpin.reg_clr)
+    {
+        if (state == 0) {
+            gpio_write(&gpio_powerpin, USB_POWER_OFF);
+        } else {
+            gpio_write(&gpio_powerpin, USB_POWER_ON);
+        }
+    }
+    else
+    {
+        /* The board does not have GPIO pin to control usb supply */
     }
     wait(0.2);
 }