diff --git a/targets/TARGET_NXP/TARGET_MCUXpresso_MCUS/TARGET_LPC/us_ticker.c b/targets/TARGET_NXP/TARGET_MCUXpresso_MCUS/TARGET_LPC/us_ticker.c
index f7469a9c50..ee0090336c 100644
--- a/targets/TARGET_NXP/TARGET_MCUXpresso_MCUS/TARGET_LPC/us_ticker.c
+++ b/targets/TARGET_NXP/TARGET_MCUXpresso_MCUS/TARGET_LPC/us_ticker.c
@@ -18,6 +18,14 @@
 #include "fsl_ctimer.h"
 #include "PeripheralNames.h"
 
+#if defined (__ARM_FEATURE_CMSE) && (__ARM_FEATURE_CMSE == 3U)
+#define CTIMER       CTIMER0
+#define CTIMER_IRQn  CTIMER0_IRQn
+#else
+#define CTIMER       CTIMER1
+#define CTIMER_IRQn  CTIMER1_IRQn
+#endif
+
 const ticker_info_t* us_ticker_get_info()
 {
     static const ticker_info_t info = {
@@ -47,13 +55,13 @@ void us_ticker_init(void) {
 
         CTIMER_GetDefaultConfig(&config);
         config.prescale = prescale - 1;
-        CTIMER_Init(CTIMER1, &config);
-        CTIMER_Reset(CTIMER1);
-        CTIMER_StartTimer(CTIMER1);
+        CTIMER_Init(CTIMER, &config);
+        CTIMER_Reset(CTIMER);
+        CTIMER_StartTimer(CTIMER);
     }
-    NVIC_SetVector(CTIMER1_IRQn, (uint32_t)us_ticker_irq_handler);
-    NVIC_EnableIRQ(CTIMER1_IRQn);
-    CTIMER1->MCR &= ~1;
+    NVIC_SetVector(CTIMER_IRQn, (uint32_t)us_ticker_irq_handler);
+    NVIC_EnableIRQ(CTIMER_IRQn);
+    CTIMER->MCR &= ~1;
 
     us_ticker_inited = true;
 }
@@ -63,7 +71,7 @@ void us_ticker_init(void) {
  * @return The current timer's counter value in ticks
  */
 uint32_t us_ticker_read(void) {
-    return CTIMER1->TC;
+    return CTIMER->TC;
 }
 
 /** Set interrupt for specified timestamp
@@ -80,32 +88,32 @@ void us_ticker_set_interrupt(timestamp_t timestamp) {
     matchConfig.outPinInitState = true;
     matchConfig.enableInterrupt = true;
 
-    CTIMER_SetupMatch(CTIMER1, kCTIMER_Match_0, &matchConfig);
+    CTIMER_SetupMatch(CTIMER, kCTIMER_Match_0, &matchConfig);
 }
 
 /** Disable us ticker interrupt
  *
  */
 void us_ticker_disable_interrupt(void) {
-    CTIMER1->MCR &= ~1;
+    CTIMER->MCR &= ~1;
 }
 
 /** Clear us ticker interrupt
  *
  */
 void us_ticker_clear_interrupt(void) {
-    CTIMER1->IR = 1;
+    CTIMER->IR = 1;
 }
 
 void us_ticker_fire_interrupt(void)
 {
-    NVIC_SetPendingIRQ(CTIMER1_IRQn);
+    NVIC_SetPendingIRQ(CTIMER_IRQn);
 }
 
 void us_ticker_free(void)
 {
-    CTIMER_StopTimer(CTIMER1);
-    CTIMER1->MCR &= ~1;
-    NVIC_DisableIRQ(CTIMER1_IRQn);
+    CTIMER_StopTimer(CTIMER);
+    CTIMER->MCR &= ~1;
+    NVIC_DisableIRQ(CTIMER_IRQn);
     us_ticker_inited = false;
 }
diff --git a/targets/TARGET_NXP/TARGET_MCUXpresso_MCUS/TARGET_LPC55S69/TARGET_LPCXpresso/mbed_overrides.c b/targets/TARGET_NXP/TARGET_MCUXpresso_MCUS/TARGET_LPC55S69/TARGET_LPCXpresso/mbed_overrides.c
index e02a69de20..44d28887fa 100644
--- a/targets/TARGET_NXP/TARGET_MCUXpresso_MCUS/TARGET_LPC55S69/TARGET_LPCXpresso/mbed_overrides.c
+++ b/targets/TARGET_NXP/TARGET_MCUXpresso_MCUS/TARGET_LPC55S69/TARGET_LPCXpresso/mbed_overrides.c
@@ -35,9 +35,15 @@ void rtc_setup_oscillator(void)
 
 uint32_t us_ticker_get_clock()
 {
+#if defined (__ARM_FEATURE_CMSE) && (__ARM_FEATURE_CMSE == 3U)
+    /* Use 12 MHz clock us ticker timer */
+    CLOCK_AttachClk(kFRO_HF_to_CTIMER0);
+    return CLOCK_GetFreq(kCLOCK_CTmier0);;
+#else
     /* Use 12 MHz clock us ticker timer */
     CLOCK_AttachClk(kFRO_HF_to_CTIMER1);
     return CLOCK_GetFreq(kCLOCK_CTmier1);;
+#endif
 }
 
 void sdio_clock_setup(void)