diff --git a/targets/TARGET_ARM_SSG/TARGET_MUSCA_B1/CMakeLists.txt b/targets/TARGET_ARM_SSG/TARGET_MUSCA_B1/CMakeLists.txt
index 9fe9672286..6d2116cde2 100644
--- a/targets/TARGET_ARM_SSG/TARGET_MUSCA_B1/CMakeLists.txt
+++ b/targets/TARGET_ARM_SSG/TARGET_MUSCA_B1/CMakeLists.txt
@@ -52,10 +52,3 @@ target_link_libraries(mbed-arm-musca-b1
         ${CMAKE_CURRENT_SOURCE_DIR}/s_veneers.o
         mbed-arm-ssg
 )
-
-add_library(mbed-arm-musca-b1-ns INTERFACE)
-
-target_link_libraries(mbed-arm-musca-b1-ns
-    INTERFACE
-        mbed-arm-musca-b1
-)
diff --git a/targets/TARGET_ARM_SSG/TARGET_MUSCA_S1/CMakeLists.txt b/targets/TARGET_ARM_SSG/TARGET_MUSCA_S1/CMakeLists.txt
index f5d6b7d71c..13309e20e0 100644
--- a/targets/TARGET_ARM_SSG/TARGET_MUSCA_S1/CMakeLists.txt
+++ b/targets/TARGET_ARM_SSG/TARGET_MUSCA_S1/CMakeLists.txt
@@ -58,10 +58,3 @@ target_link_libraries(mbed-arm-musca-s1
         ${CMAKE_CURRENT_SOURCE_DIR}/s_veneers.o
         mbed-arm-ssg
 )
-
-add_library(mbed-arm-musca-s1-ns INTERFACE)
-
-target_link_libraries(mbed-arm-musca-s1-ns
-    INTERFACE
-        mbed-arm-musca-s1
-)
diff --git a/targets/targets.json b/targets/targets.json
index f52bf24c59..3f92a9194d 100644
--- a/targets/targets.json
+++ b/targets/targets.json
@@ -4726,8 +4726,7 @@
         ],
         "extra_labels_add": [
             "ARM_SSG",
-            "MUSCA_B1",
-            "MUSCA_B1_NS"
+            "MUSCA_B1"
         ],
         "post_binary_hook": {
             "function": "ArmMuscaB1Code.binary_hook"
@@ -4742,11 +4741,6 @@
         ],
         "tfm_delivery_dir": "TARGET_ARM_SSG/TARGET_MUSCA_B1"
     },
-    "ARM_MUSCA_B1_NS": {
-        "inherits": [
-            "ARM_MUSCA_B1"
-        ]
-    },
     "ARM_MUSCA_S1": {
         "inherits": [
             "PSA_V8_M"
@@ -4784,8 +4778,7 @@
         ],
         "extra_labels_add": [
             "ARM_SSG",
-            "MUSCA_S1",
-            "MUSCA_S1_NS"
+            "MUSCA_S1"
         ],
         "post_binary_hook": {
             "function": "ArmMuscaS1Code.binary_hook"
@@ -4803,11 +4796,6 @@
             "5009"
         ]
     },
-    "ARM_MUSCA_S1_NS": {
-        "inherits": [
-            "ARM_MUSCA_S1"
-        ]
-    },
     "RZ_A1XX": {
         "inherits": [
             "Target"
diff --git a/tools/cmake/README.md b/tools/cmake/README.md
index 830d23c2cc..34a324f163 100644
--- a/tools/cmake/README.md
+++ b/tools/cmake/README.md
@@ -41,7 +41,7 @@ LPC546XX, FF_LPC546XX, CY8CKIT064B0S2_4343W, CYTFM_064B0S2_4343W, CYSBSYSKIT_01.
 
 The following Mbed boards do not have post build operations support as TFM
 is not yet supported:
-ARM_MUSCA_B1, ARM_MUSCA_B1_NS, ARM_MUSCA_S1, ARM_MUSCA_S1_NS.
+ARM_MUSCA_B1, ARM_MUSCA_S1.
 
 ### Supported toolchains