diff --git a/usb/device/targets/TARGET_Freescale/USBPhy_Kinetis.cpp b/usb/device/targets/TARGET_Freescale/USBPhy_Kinetis.cpp
index c8a55e1a66..8c277cc10e 100644
--- a/usb/device/targets/TARGET_Freescale/USBPhy_Kinetis.cpp
+++ b/usb/device/targets/TARGET_Freescale/USBPhy_Kinetis.cpp
@@ -125,6 +125,10 @@ void USBPhyHw::init(USBPhyEvents *events)
     MPU->CESR=0;
 #endif
 
+#if (defined(FSL_FEATURE_SOC_SYSMPU_COUNT) && (FSL_FEATURE_SOC_SYSMPU_COUNT > 0U))
+    SYSMPU->CESR=0;
+#endif
+
 #if defined(TARGET_KL43Z) || defined(TARGET_K22F) || defined(TARGET_K64F)
     // enable USBFS clock
     CLOCK_EnableUsbfs0Clock(kCLOCK_UsbSrcIrc48M, 48000000U);