diff --git a/targets/TARGET_NUVOTON/TARGET_M451/us_ticker.c b/targets/TARGET_NUVOTON/TARGET_M451/us_ticker.c
index 7a5deaea56..0fadea09de 100644
--- a/targets/TARGET_NUVOTON/TARGET_M451/us_ticker.c
+++ b/targets/TARGET_NUVOTON/TARGET_M451/us_ticker.c
@@ -177,7 +177,6 @@ const ticker_info_t* us_ticker_get_info()
 static void tmr0_vec(void)
 {
     us_ticker_clear_interrupt();
-    us_ticker_disable_interrupt();
 
     // NOTE: us_ticker_set_interrupt() may get called in us_ticker_irq_handler();
     us_ticker_irq_handler();
diff --git a/targets/TARGET_NUVOTON/TARGET_M480/us_ticker.c b/targets/TARGET_NUVOTON/TARGET_M480/us_ticker.c
index 911f912d8b..1441cf26b3 100644
--- a/targets/TARGET_NUVOTON/TARGET_M480/us_ticker.c
+++ b/targets/TARGET_NUVOTON/TARGET_M480/us_ticker.c
@@ -177,7 +177,6 @@ const ticker_info_t* us_ticker_get_info()
 static void tmr0_vec(void)
 {
     us_ticker_clear_interrupt();
-    us_ticker_disable_interrupt();
 
     // NOTE: us_ticker_set_interrupt() may get called in us_ticker_irq_handler();
     us_ticker_irq_handler();
diff --git a/targets/TARGET_NUVOTON/TARGET_NANO100/us_ticker.c b/targets/TARGET_NUVOTON/TARGET_NANO100/us_ticker.c
index 59628ddded..0c5160d839 100644
--- a/targets/TARGET_NUVOTON/TARGET_NANO100/us_ticker.c
+++ b/targets/TARGET_NUVOTON/TARGET_NANO100/us_ticker.c
@@ -179,7 +179,6 @@ const ticker_info_t* us_ticker_get_info()
 void TMR0_IRQHandler(void)
 {
     us_ticker_clear_interrupt();
-    us_ticker_disable_interrupt();
 
     // NOTE: us_ticker_set_interrupt() may get called in us_ticker_irq_handler();
     us_ticker_irq_handler();
diff --git a/targets/TARGET_NUVOTON/TARGET_NUC472/us_ticker.c b/targets/TARGET_NUVOTON/TARGET_NUC472/us_ticker.c
index 8d83bf813d..03e58bac60 100644
--- a/targets/TARGET_NUVOTON/TARGET_NUC472/us_ticker.c
+++ b/targets/TARGET_NUVOTON/TARGET_NUC472/us_ticker.c
@@ -176,7 +176,6 @@ const ticker_info_t* us_ticker_get_info()
 static void tmr0_vec(void)
 {
     us_ticker_clear_interrupt();
-    us_ticker_disable_interrupt();
 
     // NOTE: us_ticker_set_interrupt() may get called in us_ticker_irq_handler();
     us_ticker_irq_handler();