diff --git a/features/mbedtls/targets/TARGET_STM/TARGET_STM32F4/TARGET_STM32F439xI/mbedtls_device.h b/features/mbedtls/targets/TARGET_STM/TARGET_STM32F4/TARGET_STM32F439xI/mbedtls_device.h
index dfbc82055e..03ddf8f8ac 100644
--- a/features/mbedtls/targets/TARGET_STM/TARGET_STM32F4/TARGET_STM32F439xI/mbedtls_device.h
+++ b/features/mbedtls/targets/TARGET_STM/TARGET_STM32F4/TARGET_STM32F439xI/mbedtls_device.h
@@ -22,10 +22,12 @@
 
 #define MBEDTLS_AES_ALT
 
-#define MBEDTLS_SHA256_ALT
+/* FIXME: Don't enable SHA1, SHA256 and MD5 hardware acceleration until issue
+ * #5079 is fixed. (https://github.com/ARMmbed/mbed-os/issues/5079) */
+/* #define MBEDTLS_SHA256_ALT */
 
-#define MBEDTLS_SHA1_ALT
+/* #define MBEDTLS_SHA1_ALT */
 
-#define MBEDTLS_MD5_ALT
+/* #define MBEDTLS_MD5_ALT */
 
 #endif /* MBEDTLS_DEVICE_H */