diff --git a/tools/toolchains/__init__.py b/tools/toolchains/__init__.py
index cedd888431..0fabbaf024 100644
--- a/tools/toolchains/__init__.py
+++ b/tools/toolchains/__init__.py
@@ -78,8 +78,8 @@ class mbedToolchain:
         "Cortex-M33": ["__CORTEX_M33", "ARM_MATH_ARMV8MML", "__CMSIS_RTOS", "__MBED_CMSIS_RTOS_CM"],
         "Cortex-M33F-NS": ["__CORTEX_M33", "ARM_MATH_ARMV8MML", "DOMAIN_NS=1", "__FPU_PRESENT=1U", "__CMSIS_RTOS", "__MBED_CMSIS_RTOS_CM"],
         "Cortex-M33F": ["__CORTEX_M33", "ARM_MATH_ARMV8MML", "__FPU_PRESENT=1U", "__CMSIS_RTOS", "__MBED_CMSIS_RTOS_CM"],
-        "Cortex-M33FD-NS": ["__CORTEX_M33", "ARM_MATH_ARMV8MML", "DOMAIN_NS=1", "__FPU_PRESENT=1U", "__CMSIS_RTOS", "__MBED_CMSIS_RTOS_CM"],
-        "Cortex-M33FD": ["__CORTEX_M33", "ARM_MATH_ARMV8MML", "__FPU_PRESENT=1U", "__CMSIS_RTOS", "__MBED_CMSIS_RTOS_CM"],
+        "Cortex-M33FD-NS": ["__CORTEX_M33", "ARM_MATH_ARMV8MML", "DOMAIN_NS=1", "__FPU_PRESENT=1U", "__CMSIS_RTOS", "__MBED_CMSIS_RTOS_CM", "__DSP_PRESENT=1U"],
+        "Cortex-M33FD": ["__CORTEX_M33", "ARM_MATH_ARMV8MML", "__FPU_PRESENT=1U", "__CMSIS_RTOS", "__MBED_CMSIS_RTOS_CM", "__DSP_PRESENT=1U"],
     }
 
     MBED_CONFIG_FILE_NAME="mbed_config.h"